WebMlxiplMLX interacting protein-like [ Mus musculus(house mouse) ] Gene ID: 58805, updated on 26-Sep-2024 Download Datasets Gene Sequences (FASTA) Transcript sequences (FASTA) Protein sequences(FASTA) In addition, your package will include a detailed data report in both TSV and JSONL formats. Carbohydrate-responsive element-binding protein (ChREBP) also known as MLX-interacting protein-like (MLXIPL) is a protein that in humans is encoded by the MLXIPL gene. The protein name derives from the protein's interaction with carbohydrate response element sequences of DNA. Meer weergeven This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc / Max / Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate … Meer weergeven This gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Meer weergeven • de Luis O, Valero MC, Jurado LA (March 2000). "WBSCR14, a putative transcription factor gene deleted in Williams-Beuren syndrome: complete characterisation of the human gene and the mouse ortholog" Meer weergeven MLXIPL has been shown to interact with MLX. Meer weergeven ChREBP is translocated to the nucleus and binds to DNA after dephosphorylation of a p-Ser and a p-Thr residue by PP2A, which itself is activated by Xylulose-5-phosphate. Xu5p is produced in the pentose phosphate pathway when levels of Glucose-6-phosphate Meer weergeven
MLXIPL Antibodies
WebFurthermore, MLX-interacting protein-like (MLXIPL) is a critical glucose-responsive transcription factor that regulates lipogenic and glycolytic genes, highly controlled by the insulin-regulated glucose transporter GLUT4 in adipose tissue(15). Moreover, MLXIPL also regulates various enzymes WebCarbohydrate response element (ChRE)-binding protein is a recently discovered transcription factor that is activated in response to high glucose concentrations in liver … ritchie ottawa
Single-cell analysis reveals the intra-tumor heterogeneity and
Web20 okt. 2024 · As MLX functions as a TF in concert with its heterodimeric binding partners, MLX interacting proteins, we hypothesized that such a binding partner could also be required for male fertility. Since previous deletion of Mlxipl (encoding ChREBP) did not affect fertility [ 7 ], we gauged the requirement of Mlxip (encoding MondoA) for male fertility. WebThe conserved C terminus of MONDOA and MLX contains a cytoplasmic localization signal that directs cytoplasmic localization of the monomers and a protein-protein interaction domain that mediates interaction between MONDOA and MLX. Web14 apr. 2024 · The first step of HDMAX2 is to adjust latent factor mixed models (LFMMs) to estimate the effects of exposure, X, on a matrix M of CpG markers and the effect of each marker on outcome, Y. 24,25 LFMMs belong to a class of estimation algorithms that adjust latent factor models and that encompass surrogate variable analysis (SVA), 26 directed … smilow rail back sofa