Chemotherapy induced ovarian failure
WebJun 2, 2014 · For women who go through chemotherapy to treat breast cancer, premature ovarian failure (POF) is a common consequence. Unfortunately, POF can lead to issues such as amenorrhea (the absence of menstruation), menopausal symptoms, sexual dysfunction and infertility. WebDoes sphingosine-1-phosphate have a protective effect on cyclophosphamide- and irradiation-induced ovarian damage in the rat model?
Chemotherapy induced ovarian failure
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WebOnly RCTs that examined the effect of GnRH agonists for chemotherapy-induced ovarian failure in premenopausal women with breast cancer were selected. The rate of spontaneous resumption of menses and spontaneous pregnancy were collected. All data were analyzed by RevMan 5.3 (Cochrane Collaboration, Copenhagen, Denmark) and Stata 12.0 …
WebOct 10, 2024 · ( A) Chemotherapy drugs can damage the ovary by inducing prenatal loss of oogonia, direct loss of primordial follicles, accelerated activation of primordial follicles, … WebAug 28, 2024 · INTRODUCTION. Several toxins can cause primary hypogonadism. Some are lifesaving therapies, such as anticancer drugs and radiation therapy. Others include …
WebChemotherapy leads to a loss of fertility and reproductive endocrine function, thereby increasing the risk of premature ovarian failure (POF). Studies have suggested that the … WebJul 31, 2024 · Background Premature ovarian insufficiency (POI) is one of the most serious side effects of chemotherapy in young cancer survivors. It may not only reduce …
WebOnly RCTs that examined the effect of GnRH agonists for chemotherapy-induced ovarian failure in premenopausal women with breast cancer were selected. The rate of …
WebOf our 22 patients, 13 patients whose average duration of cyclophosphamide therapy was 24 months (range, 10 to 39) have now been without cyclophosphamide for five to 31 months. Of the 12 of this ... health2就要你健康2.0电脑版WebApr 11, 2024 · Background Chemotherapeutic drugs, particularly alkylating cytotoxics such as cyclophosphamide (CTX), play an important role to induce premature ovarian failure (POF). Hormone replacement therapy (HRT) is a widely used treatment to improve hormone secretion. However, the long-term HRT increases the risk of breast cancer and … golf edgwareWebMar 4, 2010 · Background Young cancer patients may occasionally face infertility and premature gonadal failure. Apart from its direct effect on follicles and oocytes, chemotherapy may induce ovarian toxicity via an impact on the entire ovary. The role of doxorubicin in potential ovarian failure remains obscure. Our intention was to elucidate … health2就要你健康WebSep 19, 2024 · Chemotherapy-induced premature ovarian failure (POF) in women is currently clinically irreversible. Bone marrow mesenchymal stem cells (BMSCs) are a promising cellular therapeutic strategy for POF. golf edition 30 engine bayWebDec 8, 2024 · Although the underlying mechanism is not fully understood, it is supposed that chemotherapy agents may induce either DNA damage of premature ovarian follicle or … golf editingWebOct 27, 2024 · Diagnosis. Most women have few signs of primary ovarian insufficiency, but your health care provider may suspect the condition if you have irregular periods or are having trouble conceiving. Diagnosis usually involves a physical exam, including a pelvic exam. Your provider might ask questions about your menstrual cycle, exposure to toxins, … health2就要你健康2.0官网二维码WebJul 20, 2011 · No standard strategies for preventing chemotherapy-induced ovarian failure are yet available. 12 Preclinical data have suggested that temporary ovarian suppression with a gonadotropin-releasing hormone (GnRH) analogue during chemotherapy reduces ovarian toxicity, 13,14 and phase 2 studies have shown that … health2就要你健康下载